Germline pathogenic variation impacts somatic alterations and patient outcomes in pediatric central nervous system tumors

Germline pathogenic variation impacts somatic alterations and patient outcomes in pediatric central nervous system tumors.

Corbett RJ, Kaufman RS, McQuaid SW, Vaksman Z, Phul S, Brown MA, Mason JL, Waszak SM, Zhang B, Zhong C, Blauel E, Desai H, Hausler R, Naqvi AS, Daggett JM, Sickler A, Cresswell-Clay EC, Sullivan PJ, Chroni A, Geng Z, Gonzalez EM, Zhu Y, Heath AP, Li M, Storm PB, Resnick AC, Maxwell KN, Cole KA, Waanders AJ, Bornhorst M, MacFarland SP, Rokita JL, Diskin SJ.Nat Commun. 2025 Nov 21;16(1):10282. doi: 10.1038/s41467-025-65190-4.PMID: 41271695
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